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D,L-Sulforaphane-d8

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SL-1491

D,L-Sulforaphane-d8, >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [836682-32-7]

MDL No. : MFCD28899124

Related CAS No. : [4478-93-7] of the unlabelled compound

Synonyms : 4-Methylsulfinylbutyl-d8 isothiocyanate; R,S-Sulforaphane-d8; Sulforaphan-d8

IUPAC Name : 1-Isothiocyanato-4-(methylsulfinyl)-butane-d8

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Chemical Properites
Mol. Formula :
C6H3D8NOS2
Mol. Weight :
185.34
Appearance :
Yellow oil
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : It is a deuterium labelled version of (R,S)-Sulforaphane, is a synthetic isothiocyanate. (R)-Sulforaphane is the naturally-occurring isomer, found in broccoli. This compound exhibits antioxidative, neuroprotective, anti-inflammatory, anti-atherosclerotic, neuromodulatory, cardioprotective, anticoagulant, antibiotic, anticancer chemotherapeutic, and chemopreventive activities; research suggests that the (R)-isomer may be more bioactive than the (S)-isomer. (R,S)-Sulforaphane induces activity and expression of phase II enzymes, inhibits the aryl hydrocarbon receptor, and downregulates expression of HDACs and STAT5.

References : Lee J. H. et al.: Neuroscience. Oct 10, 278, 31-39,2014; Zhang R. et al.: Int. J Mol Sci. Aug 18, 15(8),14396-410,2014; Nallasamy P. et al.: J Nutr Biochem. Aug, 25(8), 824-833, 2014; Pinz S. et al.: PLoS One. Jun 9, 9(6), e99391, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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