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Dabigatran acyl-β-D-glucuronide

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SL-2786

Dabigatran acyl-β-D-glucuronide, >95%

CAS No. : [1015167-40-4]

MDL No. : MFCD21363575

Synonyms : N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine, β-D-glucopyranuronosyl ester

IUPAC Name : (2S,3S,4S,5R,6S)-6-((3-(2-(((4-Carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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5MGRequest A Quote
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Chemical Properites
Mol. Formula :
C31H33N7O9
Mol. Weight :
647.64
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a major metabolite of Dabigatran in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys.

References : Becker B. et al.: Biochem. J., 314, 249, 1996; Bailey M. et al.: Chem. Biol. Interact., 145, 117, 2004; Blech S. et al.: Drug Metab. Dispos., 36, 386, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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