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Dabrafenib

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SI-3924

Dabrafenib, >98% (HPLC)

CAS No. : [1195765-45-7]

MDL No. : MFCD17215684

Synonyms : GSK-2118436A; GSK2118436

IUPAC Name : N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G125.00
Back Order  Estimated to ship on 04 October 2026
5G455.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H20F3N5O2S2
Mol. Weight :
519.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Dabrafenib is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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