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Dabrafenib mesylate
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SI-3925
Dabrafenib mesylate, >98% (HPLC)
CAS No. : [1195768-06-9]
MDL No. : MFCD20922872
Synonyms : GSK-2118436A mesylate; GSK2118436 mesylate
IUPAC Name : N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide mesylate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 1G | 225.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 5G | 925.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C23H20F3N5O2S2 . CH3SO2OH | Mol. Weight : 615.67 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Dabrafenib mesylate is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.
References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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