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Dacinostat

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SL-1634

Dacinostat, >98%

CAS No. : [404951-53-7]

MDL No. : MFCD09970778

IUPAC Name : (E)-3-(4-(((2-(1H-Indol-3-yl)ethyl)(2-hydroxyethyl)amino)methyl)phenyl)-N-hydroxyacrylamide

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Chemical Properites
Mol. Formula :
C22H25N3O3
Mol. Weight :
379.45
Appearance :
Light yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Dacinostat is a potent HDAC inhibitor, with an IC50 of 32 nM; also inhibits HDAC1 with an IC50 of 9 nM, and used in cancer research.

References : Atadja P. et al. Cancer Res., 64(2) 689-695, 2004; Cho Y. S. et al.: J Med. Chem., 53(7), 2952-2963,2010; Romanski A. et al.: Cell Cycle. 11(17), 3219-3226, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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