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Dactolisib

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SI-5962

Dactolisib, >98% (HPLC)

CAS No. : [915019-65-7]

MDL No. : MFCD10565944

Synonyms : NVP-BEZ235; BEZ235

IUPAC Name : 2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile

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Chemical Properites
Mol. Formula :
C30H23N5O
Mol. Weight :
469.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Dactolisib is a dual ATP-competitive PI3K and mTOR inhibitor, investigating for the potential treatment of cancer.

References : Maira S. M. et al.: Mol Cancer Ther., 7(7), 1851-1863, 2008; Roper J. et al.: PLoS One 6(9), e25132, 2011; Lee M. et al.: Clin Cancer Res., 21(14), 3204-15, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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