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CAS No. : [2891598-76-6]
Synonyms : SHR-6390 hydrochloride
IUPAC Name : 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperidin-4-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C25H30N6O2 • HCl | Mol. Weight : 483.01 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Dalpiciclib hydrochloride selectively targets CDK4 and CDK6 with low‑nanomolar potency (IC50 = 12.4 nM and 9.9 nM), resulting in effective suppression of tumor‑cell proliferation. It demonstrates strong antitumor activity in breast cancer and esophageal squamous cell carcinoma.
References : Perez-Garcia M. J. et al.: Nat. Med., 27(11), 1868-1869, 2021.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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