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Danuglipron tris

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SI-5842

Danuglipron tris, >98% (HPLC)

CAS No. : [2230198-03-3]

Synonyms : PF-06882961 tris

IUPAC Name : 2-Amino-2-(hydroxymethyl)propane-1,3-diol (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylate

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Chemical Properites
Mol. Formula :
C31H30FN5O4 . C4H11NO3
Mol. Weight :
676.75
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Danuglipron is a non-peptide agonist, activates the canonical G protein signaling activity only in the Glucagon-like peptide-1 (GLP-1) receptor with Trp33ECD. This can be used to treat type 2 diabetes mellitus (T2DM).

References : Choe J. H. et al.: Endocrinol Metab (Seoul) 36(1), 22-29, 2021; Griffith D. A. et al.: bioRxiv September 30, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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