Danusertib

SI-4884

Danusertib, >98% (HPLC)

CAS No. : [827318-97-8]

MDL No. : MFCD12024692

Synonyms : PHA-739358

IUPAC Name : (R)-N-(5-(2-Methoxy-2-phenylacetyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-4-(4-methylpiperazin-1-yl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Danusertib is an aurora kinase (AK) inhibitor for aurora A/B/C with IC₅₀ of 13 nM/79 nM/61 nM in cell-free assays, modestly potent to Abl, TrkA, c-RET and FGFR1, and less potent to Lck, VEGFR2/3, c-Kit, CDK2, etc.

References : Carpinelli P. et al.: Mol Cancer Ther., 12 Pt 1, 3158-3168, 2007; Fancelli D. et al.: J Med Chem., 49(24), 7247-7251, 2006; Gontarewicz A. et al. Blood 111(8), 4355-4364, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.