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Daprodustat

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SI-7522

Daprodustat, >98% (HPLC)

CAS No. : [960539-70-2]

Synonyms : GSK-1278863

IUPAC Name : (1,3-Dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carbonyl)glycine

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Chemical Properites
Mol. Formula :
C19H27N3O6
Mol. Weight :
393.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Daprodustat inhibits HIF‑PH enzymes with oral activity, promoting HIF stabilization and erythropoietic responses. Its pharmacological profile supports its use in studies and clinical development for CKD‑related anemia.

References : Brigandi R. A. et al.: Am J. Kidney Dis., 67(6), 861-71, 2016; Hara K. et al.: Drug Metab. Pharmacokinet., 30(6), 410-8, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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