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Daptomycin beta-isomer

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SL-7640

Daptomycin beta-isomer, >98%

CAS No. : [123180-72-3]

IUPAC Name : (3S,6S,9R,16R,19R,22S,25S,31S,32R)-31-((S)-2-((R)-4-Amino-2-((S)-2-decanamido-3-(1H-indol-3-yl)propanamido)-4-oxobutanamido)-3-carboxypropanamido)-3-(2-(2-aminophenyl)-2-oxoethyl)-25-(3-aminopropyl)-22-(carboxymethyl)-6-((R)-1-carboxypropan-2-yl)-9-(hydroxymethyl)-19,32-dimethyl-2,5,8,11,14,18,21,24,27,30-decaoxo-1-oxa-4,7,10,13,17,20,23,26,29-nonaazacyclodotriacontane-16-carboxylic acid

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Chemical Properites
Mol. Formula :
C72H101N17O26
Mol. Weight :
1620.69
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Daptomycin, which is a novel antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

References : Silverman J. A. et al.: Antimicrob Agents Chemother., 47(8), 2538-2544, 2003; Rybak M. J. et al.: Antimicrob Agents Chemother., 44(4), 1062-1066, 2000; Steenbergen J. N. et al.: J. Antimicrob Chemother., 55(3), 283-288, 2005; Louie A. et al.: Antimicrob Agents Chemother., 45(3), 845-51, 2001;Safdar N. et al.: Antimicrob Agents Chemother., 48(1), 63-8, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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