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Daridorexant

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SI-5706

Daridorexant, >98% (HPLC)

CAS No. : [1505484-82-1]

Synonyms : Nemorexant; ACT-541468

IUPAC Name : (S)-(2-(6-Chloro-7-methyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: Daridorexant is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C23H23ClN6O2
Mol. Weight :
450.93
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Daridorexant is a potent orexin receptor antagonist and has IC50s of 2 nM and 3 nM for OX1 receptor and OX2 receptor, respectively. This is used for the treatment of insomnia.

References : Dauvilliers Y. et al.: Ann Neurol ., 87(3), 347-356, 2020; 1: Ufer M. et al.: Sleep 45(3), zsab224, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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