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Darifenacin nitroso impurity

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Darifenacin nitroso impurity, >98%

IUPAC Name : (S)-2-(1-Nitrosopyrrolidin-3-yl)-2,2-diphenylacetamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C18H19N3O2
Mol. Weight :
309.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a nitrosamine impurity of Darifenacin, which is a selective M3 muscarinic receptor antagonist. Darifenacin is used to treat urinary incontinence.

References : Hegde S. S. et al.: Br. J. Pharmacol, 120(8), 1409-1418, 1997; Miller D. W. et al.: Neurourol Urodyn, 30(8), 1633-1638, 2011; Iijima K. et al.: Eur Urol., 52(3), 842-847, 2007; Haab F. et al.: Eur Urol., 45(4), 420-429, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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