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Darigabat

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SI-5053

Darigabat, >98% (HPLC)

CAS No. : [1614245-70-3]

Synonyms : PF-06372865; CVL-865

IUPAC Name : 7-Ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy-[1,1'-biphenyl]-3-yl)-7H-imidazo[4,5-c]pyridazine

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Chemical Properites
Mol. Formula :
C22H21FN4O3S
Mol. Weight :
440.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Darigabat is a potent α2/3/5 subunit selective GABAA positive allosteric modulator. Darigabat is being developed for the potential treatment of anxiety and epilepsy.

References : Owen M. R. et al.: J. Med. Chem., 62(12), 5773-5796, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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