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Darolutamide-d4

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Darolutamide-d4, >98%

CAS No. : [2484757-20-0]

IUPAC Name : N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl-1,2,2,2-d4)-1H-pyrazole-3-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C19H15D4ClN6O2
Mol. Weight :
402.88
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Darolutamide, which is a novel androgen receptor (AR) antagonist that blocks AR nuclear translocation with Ki of 11 nM. It is used in the treatment of non-metastatic castration-resistant prostate cancer in men.

References : Moilanen A. M. et al.: Sci Rep., 5, 12007, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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