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Dasatinib intermediate 4

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Dasatinib intermediate 4, >98%

CAS No. : [910297-70-0]

IUPAC Name : 3-Chloro-2-(2-((6-chloro-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamido)benzyl pivalate

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25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C21H21Cl2N5O3S
Mol. Weight :
494.39
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the synthesis of Dasatinib, which is a dual Bcr-Abl and Src family tyrosine kinase inhibitor. Dasatinib is used to treat a certain type of chronic myeloid leukemia (CML; a type of cancer of the white blood cells) as a first treatment.

References : Kovackova S. et al.: J. Med. Chem., 58(8), 3393-3410, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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