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DCZ3112

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SI-5767

DCZ3112, >98% (HPLC)

CAS No. : [2556837-25-1]

IUPAC Name : N-(4-Chloro-3-(trifluoromethyl)phenyl)-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-hydrazineyl-1,3,5-triazin-2-amine

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
We accept
Note: DCZ3112 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C15H14ClF3N8
Mol. Weight :
398.78
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DCZ3112 is a novel Hsp90 inhibitor. DCZ3112 directly bound to the N-terminal domain of Hsp90 and inhibited Hsp90-Cdc37 interaction without inhibiting ATPase activity. DCZ3112 inhibited the proliferation predominantly in HER2-positive breast cancer cells, including those resistant to the classical Hsp90 inhibitor geldanamycin, which mainly targets ATPase.

References : Chen X. et al.: Cancer Lett., 434, 70-80, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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