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Decitabine isomer 3

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Decitabine isomer 3, >98%

IUPAC Name : 1-(Diaminomethylene)-3-((2R, 4S, 5R)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)urea acetate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C7H14N4O4 • CH3CO2H
Mol. Weight :
278.27
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Decitabine, which is a cytosine analog and one potent inhibitor of DNA methyltransferase. Decitabine promotes cell cycle arrest at the G2/M phase and induces apoptosis. It demonstrates significant anticancer efficacy.

References : Nakamura M. et al.: J. Med. Virol., Jul 19, 2016: Zhang C. et al.: Clin Proteomics., July 5, 13, 14, 2016; Requena C. E. et al.: Biochem., J. Jun 20, 2016; Terse P. et al.: Int. J.Toxicol., Mar-Apr, 33(2), 75, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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