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Decoglurant

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SI-5377

Decoglurant, >98% (HPLC)

CAS No. : [911115-16-7]

MDL No. : MFCD28502084

Synonyms : Ro 49995819

IUPAC Name : 5-((7-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)ethynyl)pyridin-2-amine

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Chemical Properites
Mol. Formula :
C21H11F6N5
Mol. Weight :
447.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Decoglurant is a negative allosteric modulator of mGluR2 and mGluR3. Decoglurant is developed as an antidepressant.

References : Wilkinson S. T. et al.: Drug Discov Today 24(2), 606-615, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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