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Dehydro aripiprazole-d8 hydrochloride (piperazine-d8)

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SL-1383

Dehydro aripiprazole-d8 hydrochloride (piperazine-d8), >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1215383-78-0]

MDL No. : MFCD09840313

Related CAS No. : [1008531-60-9] of the unlabelled compound

Synonyms : Aripiprazole-d8 EP impurity E hydrochloride

IUPAC Name : 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-2(1H)-quinolinone hydrochloride

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Chemical Properites
Mol. Formula :
C23H17D8Cl2N3O2 . HCl
Mol. Weight :
490.88
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version metabolite and an impurity of Aripiprazole (Aripiprazole-d8 EP impurity E hydrochloride), which is a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.

References : Zeidan T. A. et al.: Crystal. Growth. Design., 13, 2036, 2013; Nagasaka Y. et al.: Biopharma. Drug. Dispo., 33, 304, 2012; Chen X. et al.: J. Med. Chem., 55, 7141, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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