DEL-22379

SI-7870

DEL-22379, >98% (HPLC)

CAS No. : [181223-80-3]

IUPAC Name : (Z)-N-(3-((5-Methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : DEL‑22379 targets ERK dimerization rather than catalytic activity, binding ERK2 with low‑micromolar affinity and measurable interaction at nanomolar levels. It inhibits ERK2 dimer formation with an IC₅₀ of ~0.5 µM, enabling selective interrogation of ERK dimer‑dependent signaling.

References : Herrero A. et al.: Cancer Cell, 28(2), 170-82, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.