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Denifanstat

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SI-6088

Denifanstat, >98% (HPLC)

CAS No. : [1399177-37-7]

Synonyms : TVB-2640; FASN-IN-2; ASC-40

IUPAC Name : 4-(1-(4-Cyclobutyl-2-methyl-5-(5-methyl-4H-1,2,4-triazol-3-yl)benzoyl)piperidin-4-yl)benzonitrile

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Chemical Properites
Mol. Formula :
C27H29N5O
Mol. Weight :
439.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Denifanstat inhibits FASN with sub‑micromolar potency (IC50 = 0.052 µM; EC50 = 0.072 µM) and is orally active. Its activity profile supports its use in models of fatty liver disease and in studies of FASN‑driven tumor metabolism.

References : Minhyoung L. et al.: BioRxiv, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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