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Des(oxopentyl) valsartan

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SL-4193

Des(oxopentyl) valsartan, >98%

CAS No. : [676129-92-3]

IUPAC Name : (S)-2-(((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoic acid

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Chemical Properites
Mol. Formula :
C19H21N5O2
Mol. Weight :
351.40
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Valsartan (Des(oxopentyl) valsartan impurity), which is an angiotensin II receptor antagonist for treatment of high blood pressure and heart failure.

References : Shan H. et al.: J. Cell Mol Med., 18(6),1071-1080, 2014; Wang Y. et al.: Alcohol Clin Exp Res. 38(10), 2529-4250, 2014; Sui X. et al.: J. Cell Mol Med. 19(8), 1773-1782, 2015; Jiang Y. et al.: Cardiovasc Pathol. 24(4), 224-229, 2015; Ping G. et al.: Pharmacol Biochem Behav. 124, 5-12, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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