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Desacetyl diltiazem-d3

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Desacetyl diltiazem-d3, >99% (HPLC)

Isotopic Purity : 99 atom % D

CAS No. : [1246815-32-6]

Related CAS No. : [42399-40-6] of the unlabelled compound

Synonyms : Diltiazem-d3 EP impurity F

IUPAC Name : (2S,3S)-5-(2-(Dimethylamino-d3)ethyl)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydrobenzo[b][1,4]thiazepin-4(5H)-one

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Chemical Properites
Mol. Formula :
C20H21D3N2O3S
Mol. Weight :
375.50
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Desacetyl diltiazem-d3 is a deuterium labelled version metabolite of Diltiazem, which is a Ca2+ influx inhibitor (slow channel blocker or calcium antagonist). Diltiazem-d3 EP impurity F

References : Kraus R. L. et al.: J. Biol Chem., 273(42), 27205-27212, 1998; Freitas F. et al.: Fundam Clin. Pharmacol., 29(1), 31-40, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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