Deschloro venetoclax impurity

SL-11815

Deschloro venetoclax impurity, >98%

CAS No. : [2573767-91-4]

IUPAC Name : 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity of Venetoclax, which is a highly potent, selective and orally bioavailable B-cell lymphoma 2 (BCL-2) inhibitor. It is used to treat chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and acute myeloid leukemia (AML).

References : Souers A. J. et al.: Nat Med., 19(2), 202-8, 2013; Peirs S. et al.: Blood 124(25), 3738-47, 2014; Bi C. et al.: Haematologica, 102(4), 755-764, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.