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Desethyl sildenafil

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SL-1529

Desethyl sildenafil, >98%

CAS No. : [139755-91-2]

MDL No. : MFCD24386513

Synonyms : Sildenafil EP impurity C

IUPAC Name : 5-(2-Hydroxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

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Chemical Properites
Mol. Formula :
C20H26N6O4S
Mol. Weight :
446.52
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desethyl sildenafil is a metabolite of Sildenafil, an orally active selective type 5 cGMP phosphodiesterase inhibitor.

References : Wang Z. et al.: J. Sex. Med., Nov, 10(11), 2790-2797, 2013; Li B. B. et al.: Chin. Med., J. (Engl). Sep, 124(17), 2733-2740, 2011; Moretti R. et al.: J. Neuroinflammation. Apr 28, 13(1), 95, 2016; Korkmaz M. F. et al.: Balkan Med. J. Mar, 33(2), 204-211, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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