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Desisopropoxy ceritinib hydrochloride

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SL-7609

Desisopropoxy ceritinib hydrochloride, >98%

IUPAC Name : 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(3-methyl-4-(piperidin-4-yl)phenyl)pyrimidine-2,4-diamine hydrochloride

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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We accept
Chemical Properites
Mol. Formula :
C25H30ClN5O2S . HCl
Mol. Weight :
536.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of of Ceritinib, which is a second-generation, orally active, selective inhibitor of anaplastic lymphoma kinase (ALK). It blocks autophosphorylation of ALK, which inhibits downstream signaling proteins and prevents proliferation of ALK- dependent cancer cells. It is used for the treatment of non-small cell lung cancer.

References : Flick C. A. et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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