Desisopropyl ipatasertib dihydrochloride

SI-5284

Desisopropyl ipatasertib dihydrochloride, >98% (HPLC)

CAS No. : [1001264-73-8]

Synonyms : Ipatasertib-NH2 dihydrochloride; GDC-0068-NH2 dihydrochloride; RG7440-NH2 dihydrochloride

IUPAC Name : (S)-3-Amino-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)propan-1-one dihydrochloride

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Desisopropyl ipatasertib dihydrochloride is a ligand for target protein AKT for PROTAC (INY-03-041). INY-03-041 is composed of Ipatasertib-NH2, a ten-hydrocarbon linker, and a CRBN ligand Lenalidomide for E3 ubiquitin ligase.

References : You I. et al. Cell Chem Biol., 27(1), 66-73.e7, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.