Desmethyl cariprazine

SI-5011

Desmethyl cariprazine, >98% (HPLC)

CAS No. : [839712-15-1]

IUPAC Name : 1-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-3-methylurea

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Desmethyl cariprazine is an active metabolite of Cariprazine. Cariprazine, an antipsychotic drug candidate, exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).

References : Seneca N. et al.: Psychopharmacology (Berl). 218(3), 579, 2011; Kiss B. et al. J Pharmacol Exp Ther. 333(1), 328-340, 2010; Zimnisky R. et al.: Psychopharmacology (Berl), 226(1), 91-100,2013; Gao Y. et al.: Pharmacol Res Perspect., 3(1), e00073, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.