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Desmethyl cariprazine-d8

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Desmethyl cariprazine-d8, >98%

CAS No. : [1308278-85-4]

IUPAC Name : 1-((1r,4r)-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl-2,2,3,3,5,5,6,6-d8)ethyl)cyclohexyl)-3-methylurea

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Chemical Properites
Mol. Formula :
C20H22D8Cl2N4O
Mol. Weight :
421.44
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
3% TFA in MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version impurity of Cariprazine, which is an active metabolite of Cariprazine. It is an antipsychotic drug candidate.

References : Seneca N. et al.: Psychopharmacology (Berl). 218(3), 579, 2011; Kiss B. et al. J. Pharmacol Exp Ther. 333(1), 328-340, 2010; Zimnisky R. et al.: Psychopharmacology (Berl), 226(1), 91-100, 2013; Gao Y. et al.: Pharmacol Res Perspect., 3(1), e00073, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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