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Desmethyl imatinib-d4

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Desmethyl imatinib-d4, >98% (HPLC)

Isotopic Purity : 98 atom % D

Synonyms : Imatinib-d4 EP impurity C; N-Desmethyl gleevec-d4; CGP-74588-d4; Norimatinib-d4; STI 509-00-d4

IUPAC Name : N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-(piperazin-1-ylmethyl)benzamide-d4

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C28H25D4N7O
Mol. Weight :
483.6
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Desmethyl imatinib-d4 (Imatinib-d4 EP impurity C) is a deuterium labelled version metabolite of Imatinib, which is a tyrosine kinases inhibitor for the treatment of cancer.

References : Heinrich M. C. et al.: Blood. 96(3), 925-932, 2000; Guida T. et al.: Clin Cancer Res. 13(11), 3363-3369, 2007; Okuda K. et al.: Blood. 97(8), 2440-2448, 2001; Yao J. C. et al.: Clin Cancer Res. 13(1), 234-240, 2007; Sun X. C. et al.: World J. Gastroenterol. 19(15), 2340-2347, 2013; Yildiz C. et al.: Eur J. Obstet Gynecol Reprod Biol. 197, 159-163, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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