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Desmethyl loperamide-d3

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SL-3470

Desmethyl loperamide-d3, >98% (CP)

Isotopic Purity : 99 atom % D

CAS No. : [1189488-17-2]

IUPAC Name : 4-(4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl)-N-(methyl-d3)-2,2-diphenylbutanamide

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Chemical Properites
Mol. Formula :
C28H28D3ClN2O2
Mol. Weight :
466.03
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desmethyl loperamide-d3 is a deuterium labelled version an impurity of Loperamide (Desmethyl loperamide), which is a selective μ-opioid receptor agonist, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.

References : DeHaven-Hudkins D. L. et al.: J. Pharmacol Exp Ther., 289(1), 494-502, 1999; Quinney S. K. et al. J. Pharmacol Exp Ther., 313(3), 1011-1016, 2005; Church J. et al.: Mol. Pharmacol., 45(4), 747-757, 1994.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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