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Desmethyl tepotinib

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Desmethyl tepotinib, >98%

CAS No. : [1103506-82-6]

IUPAC Name : 3-(6-Oxo-1-(3-(5-(piperidin-4-ylmethoxy)pyrimidin-2-yl)benzyl)-1,6-dihydropyridazin-3-yl)benzonitrile

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C28H26N6O2
Mol. Weight :
478.56
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tepotinib, which is an orally active, highly selective, reversible ATP-competitive inhibitor of c-Met. Tepotinib effectively inhibits c-Met phosphorylation and promotes autophagy. Additionally, it has demonstrated antitumor activity.

References : Bladt F. et al.: Clin Cancer Res., 19(11), 2941-2951, 2013; Zhan N. et al.: Gene Expr., 18(2), 135-147, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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