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Desoxopentyl valsartan

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Desoxopentyl valsartan, >98%

CAS No. : [676129-92-3]

MDL No. : MFCD30342453

Synonyms : N-[[2’-(2H-Tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-L-valine; N-[[2’-(1H-Tetrazol-5-yl)[1,1’-biphenyl]-4-yl]methyl]-L-valine; Valsartan desvaleryl impurity

IUPAC Name : (S)-2-(((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoic acid

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Chemical Properites
Mol. Formula :
C19H21N5O2
Mol. Weight :
351.40
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desoxopentyl valsartan is a key starting material in the preparation of Valsartan or an impurity (Valsartan desvaleryl impurity) during process, which is an angiotensin II receptor antagonist for the treatment of high blood pressure and heart failure.

References : Shan H. et al.: J. Cell Mol Med., 18(6),1071-1080, 2014; Wang Y. et al.: Alcohol Clin Exp Res. 38(10), 2529-4250, 2014; Sui X. et al.: J. Cell Mol Med. 19(8), 1773-1782, 2015; Jiang Y. et al.: Cardiovasc Pathol. 24(4), 224-229, 2015; Ping G. et al.: Pharmacol Biochem Behav. 124, 5-12, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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