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Desphenyl tenofovir alafenamide-d7 (isopropyl-d7)

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SL-1880

Desphenyl tenofovir alafenamide-d7 (isopropyl-d7), >96% (CP)

Related CAS No. : [851456-00-3] of the unlabelled compound

IUPAC Name : P-((((R)-1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)-N-((S)-1-oxo-1-((propan-2-yl-d7)oxy)propan-2-yl)phosphonamidic acid

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Chemical Properites
Mol. Formula :
C15H18D7N6O5P
Mol. Weight :
407.41
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desphenyl tenofovir alafenamide-d7 is a deuterium labelled form of Desphenyl tenofovir alafenamide, which belongs to a group of tenofovir diesters compounds, which can inhibit HIV-1 virus replication. Desphenyl tenofovir alafenamide can also be used to investigate the effect of oral absorption and lymphoid cell loading of GS-7340 (a prodrug of Tenofovir).

References : Babusis D. et al.: Mol. Pharm., 10, 459, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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