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Dexamethasone EP impurity I

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SL-3059

Dexamethasone EP impurity I, >98%

CAS No. : [14622-47-0]

Synonyms : 9,11α-Epoxy-17,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione; 9,11-Epoxy-9H-cyclopenta[a]phenanthrene pregna-1,4-diene-3,20-dione ; (11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

IUPAC Name : (4aS,4bR,5aR,6aS,7R,8R,9aS,9bS)-7-Hydroxy-7-(2-hydroxyacetyl)-4a,6a,8-trimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one

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Chemical Properites
Mol. Formula :
C22H28O5
Mol. Weight :
372.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dexamethasone (Dexamethasone EP impurity I), which is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.

References : LaLone C. A. et al.: Environ Toxicol Chem. 31(3), 611-622, 2012; Adcock I. M. et al.: Br. J. Pharmacol. 127(4), 1003-1011, 1999; Rocksén D. et al.: Clin Exp Immunol. 122(2), 249-256, 2000; Roussel D. et al.: FEBS Lett., 541(1-3), 75-79, 2003; Maher H. M. et al.: J. Pharm Biomed Anal.,124, 216-227, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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