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Dexamethasone impurity

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Dexamethasone impurity, >98%

CAS No. : [4619-61-8]

IUPAC Name : (8S,9R,10S,11S,13S,14S,16R,17R)-17-(2,2-Dihydroxyacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

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Chemical Properites
Mol. Formula :
C22H29FO6
Mol. Weight :
408.46
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dexamethasone, which is a type of corticosteroid medication. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, and along with antibiotics in tuberculosis.

References : LaLone C. A. et al.: Environ Toxicol Chem. 31(3), 611-622, 2012; Adcock I. M. et al.: Br. J. Pharmacol. 127(4), 1003-1011, 1999; Rocksén D. et al.: Clin Exp Immunol. 122(2), 249-256, 2000; Roussel D. et al.: FEBS Lett., 541(1-3), 75-79, 2003; Maher H. M. et al.: J. Pharm Biomed Anal.,124, 216-227, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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