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DG-051

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SI-6414

DG-051, >98% (HPLC)

CAS No. : [929915-58-2]

IUPAC Name : (S)-4-(2-((4-(4-Chlorophenoxy)phenoxy)methyl)pyrrolidin-1-yl)butanoic acid hydrochloride

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Chemical Properites
Mol. Formula :
C21H24ClNO4 • HCl
Mol. Weight :
426.3
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DG-051 selectively inhibits LTA4H with an IC50 of 47 nM, effectively reducing leukotriene B4 production in biochemical assays. It is a valuable tool for probing LTA4H‑dependent inflammatory signaling.

References : Sandanayaka V. et al.: J. Med. Chem., 53(2), 573-85, 2010; Enache L. A. et al.: Bioorg. Med. Chem. Lett., 19(22), 6275-9, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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