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DHODH-IN-21

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SI-7140

DHODH-IN-21, >98% (HPLC)

CAS No. : [2450341-39-4]

IUPAC Name : (S)-N-(2-Chloro-4-methylpyridin-3-yl)-6-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)nicotinamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H19ClF4N6O4
Mol. Weight :
518.85
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an orally active DHODH inhibitor with low‑nanomolar potency (IC50 = 1.1 nM). It displays notable anticancer effects and is well suited for mechanistic and translational studies in AML.

References : Cisar J. S. et al.: J .Med. Chem., 65(16), 11241-11256, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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