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Di-POC Tenofovir dimer

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Di-POC Tenofovir dimer, >93% (HPLC)

CAS No. : [1962114-92-6]

IUPAC Name : [[Hydroxy[[[[2R]-1-[6-[[[[9-[[2R]-2-[[hydroxyhydrophosphoryl]methoxy]propyl]-9H-purin-6-yl]amino]methyl]amino]-9H-purin-9-yl]propan-2-yl]oxy]methyl]phosphoryl]bis[oxy]]bis[methylene] diisopropyl dicarbonate

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Chemical Properites
Mol. Formula :
C29H44N10O14P2
Mol. Weight :
818.67
Appearance :
Off-white gummy thick syrup
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a dimer of Tenofovir disoproxil, which is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.

References : Murphy R. A. et al. Int. J. Mol. Sci. 18(3), 2017; Musumeci G. et al. Sci. Rep. 7, 41018, 2017; Wahl A. et al. Sci. Rep. 7, 41098, 2017; Menne S. et al.: J. Antimicrob Agents Chemother., 49(7), 2720-2728, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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