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Diclofenac isopropyl ester

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SL-5718

Diclofenac isopropyl ester, >98%

CAS No. : [66370-79-4]

IUPAC Name : Isopropyl 2-(2-((2,6-dichlorophenyl)amino)phenyl)acetate

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Chemical Properites
Mol. Formula :
C17H17Cl2NO2
Mol. Weight :
338.23
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog of Diclofenac, which is a nonsteroidal anti-inflammatory drug that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions. It inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) with relative equipotency.

References : Cho M. et al.: FEBS Lett., 579(20), 4213-4218, 2005; Lee H. M. et al.: Brain Res., 992(1), 120-127, 2003; Triebskorn R. et al.: Aquat Toxicol., 68(2), 151-166, 2004; Petrescu I. et al.: Biochim Biophys Acta 1318(3), 385-394, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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