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Diethyl-lodoxamide

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SI-7672

Diethyl-lodoxamide, >98% (HPLC)

CAS No. : [53882-13-6]

IUPAC Name : Diethyl 2,2'-((2-chloro-5-cyano-1,3-phenylene)bis(azanediyl))bis(2-oxoacetate)

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Chemical Properites
Mol. Formula :
C15H14ClN3O6
Mol. Weight :
367.74
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Diethyl‑Lodoxamide potently activates GPR35 in humans, mice, and rats with similar potency profiles and shows marked anti‑inflammatory effects in vivo. In DSS‑induced IBD mouse models, it reduces disease severity more effectively than 5‑ASA. Its optimized pharmaceutical characteristics make it a promising tool compound for GPR35‑targeted drug‑design and IBD research.

References : Song Z. et al.: Bioorg. Med. Chem., 96, 117511, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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