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Digoxin EP impurity G

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SL-6667

Digoxin EP impurity G, >98%

CAS No. : [55576-67-5]

Synonyms : Neodigoxin

IUPAC Name : 4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-(((2R,4R,5S,6R)-5-(((2S,4S,5S,6R)-5-(((2S,4S,5S,6R)-4,5-Dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one

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Chemical Properites
Mol. Formula :
C41H64O14
Mol. Weight :
780.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Digoxin (Digoxin EP impurity G), which is a classical Na, K-ATPase inhibitor, with selectivity for the α2β3 isoform over the common α1β1 isoform, used in the treatment of atrial fibrillation and heart failure.

References : Katz A. et al.: Proc Natl Acad Sci U S A. 112(44), 13723-8, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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