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Dihydrodiol Ibrutinib-d5

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Dihydrodiol Ibrutinib-d5, >98% (CP)

Related CAS No. : [1226872-27-0] of the unlabelled compound

Synonyms : PCI 45227-d5

IUPAC Name : 1-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one-d5

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG680.00
In Stock  Estimated to ship on 20 September 2026
10MG1280.00
In Stock  Estimated to ship on 20 September 2026
25MG2980.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C25H21D5N6O4
Mol. Weight :
479.54
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Dihydrodiol Ibrutinib-d5 is a deuterium labelled version metabolite of Ibrutinib, which is a selective, irreversible Btk inhibitor.

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107(29), 13075-13080, 2010; Herman S. E. et al.: Blood. 117(23), 6287-6296, 2011; Chang B. Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7(1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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