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Dihydroxy zanubrutinib

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Dihydroxy zanubrutinib, >98%

IUPAC Name : 7-(1-(2,3-Dihydroxypropanoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide

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Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C27H31N5O5
Mol. Weight :
505.57
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a impurity / metabolite of Zanubrutinib, which is a potent, specific and irreversible BTK inhibitor that has been shown to have a lower off-target inhibitory activity on other kinases, including ITK, JAK3 and EGFR. Zanubrutinib is used to treat mantle cell lymphoma.

References : Tam C. et al.: Blood 126, 832, 2015; Li N. et al.: AACR Cancer Res., 75(15 Suppl), Abstract nr 2597, 2015; Wu J. et al.: J. Hematol Oncol., 9(1), 80, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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