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Diisopropyl tenofovir

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Diisopropyl tenofovir, >98%

CAS No. : [160616-04-6]

Synonyms : Tenofovir alafenamide impurity G

IUPAC Name : Diisopropyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

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Chemical Properites
Mol. Formula :
C15H26N5O4P
Mol. Weight :
371.38
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tenofovir, which is a new HIV inhibitor with further activity against HBV. It was explored in 12 HBV/HIV-co-infected patients with detectable levels of serum HBV-DNA, despite receiving a lamivudine-containing antiretroviral regimen.Tenofovir is very effective at reducing HBV-DNA levels in HIV/HBV-co-infected patients carrying either wild-type or lamivudine-resistant viruses.

References : Nunez M. et.al.: AIDS 16(17), 2352, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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