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DNL-747

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SI-8000

DNL-747, >98% (HPLC)

Synonyms : SAR-443060

IUPAC Name : 5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C13H12ClN3O2
Mol. Weight :
277.71
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DNL‑747 is a selective, orally bioavailable RIPK1 inhibitor designed to block RIPK1‑mediated inflammatory and necroptotic signaling. It shows strong target engagement, reduces pro‑inflammatory cytokine production, and has been evaluated for neurodegenerative and inflammatory disease research where RIPK1 pathway suppression is therapeutically relevant.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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