Docetaxel-d5

SL-4338

Docetaxel-d₅, >98% (HPLC)

Isotopic Purity : 99 atom % D

Synonyms : RP-56976-d₅; NSC-628503-d₅

IUPAC Name : (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate-d₅

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 20 September 2026
10MG	Request A Quote		Back Order	Estimated to ship on 20 September 2026
25MG	Request A Quote		Back Order	Estimated to ship on 20 September 2026

Applications : Docetaxel-d₅ is a deuterium labelled version of Docetaxel, an analog of Paclitaxel. It is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules, used to treat a number of types of cancers. This includes breast cancer, head and neck cancer, stomach cancer, prostate cancer and non-small-cell lung cancer.

References : Attia R. T. et al.: Peer J. 4, e2168, 2016; Che C. L. et al.: Int. J. Clin. Exp Pathol., 6(8), 1538-48, 2013; Obi-Ioka Y. et al.: J. Pharmacol Exp Ther., 347(1), 242-8, 2013; Li C. et al.: J. Pharm Biomed Anal., 128, 286-93, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.