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Dolutegravir impurity E

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SL-7682

Dolutegravir impurity E, >98%

CAS No. : [1485081-26-2]

IUPAC Name : (4R,12aS)-7-Hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

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Chemical Properites
Mol. Formula :
C13H15N3O5
Mol. Weight :
293.28
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dolutegravir (Dolutegravir impurity E), which is a second-generation HIV integrase strand transfer inhibitor (INSTI), used to treat HIV/AIDS.

References : Charpentier C. et al.: AIDS 24(17), 2753-275, 2010; Kobayashi M. et al.: Antimicrob Agents Chemother., 55(2), 813-21, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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