Dosimertinib-d5

SI-6082

Dosimertinib-d₅, >98% (HPLC)

CAS No. : [2403760-70-1]

IUPAC Name : N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(methyl-d₃)-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide-3,3-d₂

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Dosimertinib‑d₅ is a deuterated analog of the third‑generation EGFR inhibitor osimertinib, used as a stable‑label reference standard for analytical and PK studies. It retains the potent EGFR‑TKI activity of the parent compound while enabling enhanced mass‑spectrometric discrimination in ADME and bioanalytical workflows.

References : Chen C. et al.: Eur J. Med. Chem., 247, 115023, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.